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Question 18.3: Coenzymes Describe the reactive part of each of the followin...

Coenzymes

Describe the reactive part of each of the following coenzymes and the way each participates in metabolic pathways:

a. FAD                     b. NAD^+

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a. When two nitrogen atoms in the flavin accept 2H (2H^+ and 2  e^-), FAD is reduced to FADH_2. The FAD coenzyme participates in oxidation reactions that produce a carbon– carbon (C=C) double bond.

b. When a carbon atom in the nicotinamide accepts 2H (2H^+ and 2  e^-), NAD^+ is reduced to NADH + H^+. The NAD^+ coenzyme participates in oxidation reactions that produce a carbon–oxygen (C=O) double bond.

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