Chemiosmotic Model
Consider the process of proton pumping in the chemiosmotic model.
a. What changes in pH take place in the mitochondrial matrix and in the intermembrane space?
b. How do the protons return to the matrix?
c. How is energy obtained for the synthesis of ATP?
a. The process of proton pumping “pushes” protons (H^{+}) out of the mitochondrial matrix and into the intermembrane space. The loss of H^{+} increases the pH in the matrix whereas the increase of protons (H ^{+}) in the intermembrane space decreases its pH.
b. Protons return to the matrix by passing through ATP synthase.
c. The energy from the proton flow through ATP synthase is used to synthesize ATP.