Question 18.CC.6: Fates of Pyruvate When is pyruvate converted to each of the ......

Chemistry: An Introduction to General, Organic, and Biological Chemistry [1013382]

Fates of Pyruvate
When is pyruvate converted to each of the following?
a. acetyl CoA b. lactate

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a. Pyruvate is converted to acetyl CoA and NADH under aerobic conditions when oxygen is plentiful. The NADH is oxidized back to NAD $^{+}$ to allow glycolysis to continue.
b. Pyruvate is converted to lactate and NAD $^{+}$ under anaerobic conditions, which provides NAD $^{+}$ for glycolysis.

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