Question 17.SP.7: Mutations An mRNA has the sequence of codons —CCC—AGA—GCC— .......
Mutations
An mRNA has the sequence of codons —CCC—AGA—GCC— .If a base substitution in the DNA changes the mRNA codon of AGA to GGA, how is the amino acid sequence affected in the resulting protein?
Step-by-Step
The initial mRNA sequence of —CCC—AGA—GCC— codes for the following amino acids: proline, arginine, and alanine. When the mutation occurs, the new sequence of mRNA codons is —CCC—GGA—GCC—,which codes for proline, glycine, and alanine. The basic amino acid arginine is replaced by nonpolar glycine.
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