Question 20.39: Pivalic acid, (CH₃)₃CCO₂H, can be prepared from tert-butyl c......
Pivalic acid, (CH₃)₃CCO₂H, can be prepared from tert-butyl chloride. What method should be used?
Step-by-Step
First, prepare the Grignard reagent using magnesium and ether. Second, add the Grignard reagent to carbon dioxide, followed by acidification in workup. The alternate method of displacing bromide ion by cyanide ion to give a nitrile cannot be accomplished with a tertiary halide.
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