Question 18.CC.7: Reactions of Part 1 of the Citric Acid Cycle a. What is the ......

Chemistry: An Introduction to General, Organic, and Biological Chemistry [1013382]

Reactions of Part 1 of the Citric Acid Cycle
a. What is the function of reaction 1 in the citric acid cycle?
b. Why does citrate undergo isomerization in reaction 2?

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a. Reaction 1 in the citric acid cycle combines an acetyl group (2C) with oxaloacetate (4C) to produce citrate (6C).
b. In reaction 2, citrate, a tertiary alcohol, isomerizes to isocitrate, a secondary alcohol that can be oxidized.

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