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Question 18.33: Reduction of 5-chloro-2-pentanone by NADPH in an enzyme-cata......

Reduction of 5-chloro-2-pentanone by NADPH in an enzyme-catalyzed reaction yields (S)-5-chloro-2-pentanol. From which face does the hydrogenation occur?

لقطة الشاشة 2023-08-15 224252
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The S-enantiomer can only be produced if the NADPH adds hydride to the si face of the carbonyl group.

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