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Question 11.1: The body mass index (BMI) and the systolic blood pressure of......

The body mass index (BMI) and the systolic blood pressure of 6 people were measured to study a cardiovascular disease. The data are as follows:

(a) The research hypothesis is that a high BMI relates to a high blood pressure. Estimate the linear model where blood pressure is the outcome and BMI is the covariate. Interpret the coefficients.
(b) Calculate R² to judge the goodness of fit of the model.

Body mass index 26 23 27 28 24 25
Systolic blood pressure 170 150 160 175 155 150
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(a) Calculating \bar{x}=\frac{1}{6}\left(26 + 23 + 27 + 28 + 24 + 25\right) = 25.5 and \bar{y}=\frac{1}{6}\left(170 + 150 + 160 + 175 + 155 + 150\right) = 160, we obtain the following table needed for the estimation of \hat{\alpha } and \hat{\beta }

With \Sigma _{i}v_{i}=\Sigma _{i}\left(x_{i}-\bar{x} \right) \cdot \left(y_{i}-\bar{y} \right) = 80, it follows that S_{xy} = 80. Moreover, we get S_{xx} =\Sigma _{i}\left(x_{i}-\bar{x} \right)^{2} = 17.5 and S_{yy} = \Sigma _{i} \left(y_{i}-\bar{y} \right)^{2} = 550. The parameter estimates are therefore

\hat{\beta } =\frac{S_{xy}}{S_{xx}} =\frac{80}{17.5} \approx 4.57,
\hat{\alpha }=\bar{y} -\hat{\beta }\bar{x} =160 − 4.57 · 25.5 = 43.465.

A one-unit increase in the BMI therefore relates to a 4.57 unit increase in the blood pressure. The model suggests a positive association between BMI and systolic blood pressure. It is impossible to have a BMI of 0; therefore, \hat{\alpha } cannot be interpreted meaningfully here.

(b) Using (11.14), we obtain R² as

R^{2}=r^{2}=\left(\frac{S_{xy}}{\sqrt{S_{xx}S_{yy}} } \right)^{2} = \left(\frac{80}{\sqrt{17.5 · 550} } \right)^{2}\approx 0.66.

Thus 66%of the data’s variability can be explained by the model. The goodness of fit is good, but not perfect.

Body mass index Systolic blood pressure v_{i}
x_{i} x_{i}-\bar{x} \left(x_{i}-\bar{x}\right)^{2} y_{i} y_{i}-\bar{y} \left(y_{i}-\bar{y}\right)^{2}
26 0.5 0.25 170 10 100 5
23 -2.5 6.25 150 -10 100 25
27 1.5 2.25 160 0 0 0
28 2.5 6.25 175 15 225 37.5
24 -1.5 2.25 155 -5 25 7.5
25 -0.5 0.25 150 -10 100 5
Total 153 17.5 960 550 80

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