Question 22.3: (a) Draw the structure of a dinucleotide formed by joining t...
(a) Draw the structure of a dinucleotide formed by joining the 3 ‘ -OH group of AMP to the 5 ‘ -phosphate in GMP. (b) Label the 5 ‘ and 3 ‘ ends. (c) Name the dinucleotide.
Analysis
Draw the structure of each nucleotide, including the sugar, the phosphate bonded to C5 ‘ , and the base at C1 ‘ . In this case the sugar is ribose since the names of the mononucleotides do not contain the prefix deoxy. Bond the 3 ‘ -OH group to the 5 ‘ -phosphate to form the phosphodiester bond. The name of the dinucleotide begins with the nucleotide that contains the free phosphate at the 5 ‘ end.
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a. and b.
c. Since polynucleotides are named beginning at the 5 ‘ end, this dinucleotide is named AG.
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