Question 24.2: Analyze the following reaction by considering the functional...
Analyze the following reaction by considering the functional groups that change, the coenzyme utilized, and the name of the enzyme.
Analysis
• Consider the functional groups that are added or removed as a clue to the type of reaction.
• Classify the reagent—that is, any coenzyme or other reactant—as to the type of reaction it undergoes. For example, \mathrm{NAD}^{+} is an oxidizing agent, while NADH is a reducing agent.
ATP transfers phosphate groups to substrates, while ADP accepts phosphate groups from substrates.
• Use the name of the enzyme as a clue to the reaction type.
A phosphate group is removed from the reactant to give 3-phosphoglycerate. This phosphate is transferred to the nucleoside diphosphate ADP to form the nucleoside triphosphate ATP. Since kinase enzymes catalyze the addition or removal of phosphates, the enzyme used for the reaction is phosphoglycerate kinase. No coenzyme is used here; the reaction does not involve oxidation, reduction, or thioester synthesis.