Question 24.3: How many ATP will be produced from the β oxidation of palmit...

General, Organic, and Biological Chemistry: Structures of Life

How many ATP will be produced from the β oxidation of palmitic acid, a $C_{16}$ saturated fatty acid?

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Palmitic acid ( $C_{16}$ ) requires seven β oxidation cycles, which produce seven NADH and seven $FADH_{2}$ . The total number of acetyl CoA is eight. The activation of palmitic acid decreases the total produced by two ATP.

ANALYZE THE PROBLEM	Given	Need	Connect
ANALYZE THE PROBLEM	β oxidation of palmitic acid $(C_{16})$	total ATP produced	NADH, $FADH_{2}$ , acetyl CoA

ATP Production from β Oxidation of Palmitic Acid (16:0)
Activation	– 2 ATP
8 Acetyl CoA (16 C atoms $\times$ 1 acetyl CoA/2 C atoms)
8 acetyl CoA $\times$ 10 ATP/acetyl CoA	80 ATP
7 β Oxidation Cycles
7 NADH $\times$ 2.5 ATP/NADH	17.5 ATP
$7 FADH_{2} \times 1.5 ATP/FADH_{2}$	10.5 ATP
Total 106 ATP

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