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Question 25.2: Statistical mechanics can be used to predict the dependence ...

Statistical mechanics can be used to predict the dependence of protein folding on temperature. Consider a polypeptide chain consisting of six beads having the energy ladder shown below, where the energy increment of the unfolded states, \varepsilon_{0}, is positive. You are asked to answer the following questions:

(a) What is the degeneracy of each energy state?
(b) What is the Canonical partition function of the polypeptide chain?
(c) What are the probabilities of observing the polypeptide chain in each of the three states as a function of temperature? Discuss the low-temperature and the hightemperature limits.

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