Question 17.sp.9: What polypeptide would be synthesized from the following tem...

What polypeptide would be synthesized from the following template strand of DNA:
CGG TGT CTT TTA?
Analysis
To determine what polypeptide is synthesized from a DNA template, two steps are needed. First use the DNA sequence to determine the transcribed mRNA sequence: C pairs with G, T pairs with A, and A (on DNA) pairs with U (on mRNA). Then use the codons in Table 17.3 to determine what amino acids are coded for by a given codon in mRNA.

Table 17.3 The Genetic Code—Triplets in Messenger RNA

Third Base
(3′ end)
Second Base First Base
(5′ end)
G A C U
U Cys UGU Tyr UAU Ser UCU Phe UUU U
C Cys UGC Tyr UAC Ser UCC Phe UUC
A Stop UGA Stop UAA Ser UCA Leu UUA
G Trp UGG Stop UAG Ser UCG Leu UUG
U Arg CGU His CAU Pro CCU Leu CUU C
C Arg CGC His CAC Pro CCC Leu CUC
A Arg CGA Gln CAA Pro CCA Leu CUA
G Arg CGG Gln CAG Pro CCG Leu CUG
U Ser AGU Asn AAU Thr ACU Ile AUU A
C Ser AGC Asn AAC Thr ACC Ile AUC
A Arg AGA Lys AAA Thr ACA Ile AUA
G Arg AGG Lys AAG Thr ACG Met AUG
U Gly GGU Asp GAU Ala GCU Val GUU G
C Gly GGC Asp GAC Ala GCC Val GUC
A Gly GGA Glu GAA Ala GCA Val GUA
G Gly GGG Glu GAG Ala CGG Val GUG
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17.8

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