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Question 22.4: Sections A, C, and E of the following base sequence section ......

Sections A, C, and E of the following base sequence section of a DNA template strand are exons, and sections B and D are introns.

a. What is the structure of the hnRNA transcribed from this template?
b. What is the structure of the mRNA obtained by splicing the hnRNA?

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a. The base sequence in the hnRNA will be complementary to that of the template DNA, except that U is used in the RNA instead of T. The hnRNA will have a directionality antiparallel to that of the DNA sequence.

b. In the splicing process, introns are removed and the exons combined to give the mRNA.

Introns and exons are actually never as short as those given in this simplified example.

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