Question 4.21: Marecek and colleagues developed a new electrochemical metho...
Marecek and colleagues developed a new electrochemical method for the rapid quantitative analysis of the antibiotic monensin in the fermentation vats used during its production.^9 The standard method for the analysis, which is based on a test for microbiological activity, is both difficult and time-consuming. As part of the study, samples taken at different times from a fermentation production vat were analyzed for the concentration of monensin using both the electrochemical and microbiological procedures. The results, in parts per thousand (ppt),* are reported in the following table.
Sample | Microbiological | Electrochemical |
1 | 129.5 | 132.3 |
2 | 89.6 | 91.0 |
3 | 76.6 | 73.6 |
4 | 52.2 | 58.2 |
5 | 110.8 | 104.2 |
6 | 50.4 | 49.9 |
7 | 72.4 | 82.1 |
8 | 141.4 | 154.1 |
9 | 75.0 | 73.4 |
10 | 34.1 | 38.1 |
11 | 60.3 | 60.1 |
Determine whether there is a significant difference between the methods at α = 0.05.
*1 ppt is equivalent to 0.1%.
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