Question 24.2: Predicting the Amino Acid Sequence Transcribed from DNA What...
Predicting the Amino Acid Sequence Transcribed from DNA
What amino acid sequence is coded by the following segment of a DNA sense strand?
(5′) CTA-ACT-AGC-GGG-TCG-CCG (3′)
Strategy
The mRNA produced during translation is a copy of the DNA sense strand, with each T replaced by U. Thus, the mRNA has the sequence
(5′) CUA-ACU-AGC-GGG-UCG-CCG (3′)
Each set of three bases forms a codon, whose meaning can be found in Table 24.1.
| TABLE 24.1 | |||||
| Codon Assignments of Base Triplets | |||||
| Third base (3′ end) | |||||
| First base (5′ end) | Second base | U | C | A | G |
| U | U | Phe | Phe | Leu | Leu |
| C | Ser | Ser | Ser | Ser | |
| A | Tyr | Tyr | Stop | Stop | |
| G | Cys | Cys | Stop | Trp | |
| C | U | Leu | Leu | Leu | Leu |
| C | Pro | Pro | Pro | Pro | |
| A | His | His | Gln | Gln | |
| G | Arg | Arg | Arg | Arg | |
| A | U | Ile | Ile | Ile | Met |
| C | Thr | Thr | Thr | Thr | |
| A | Asn | Asn | Lys | Lys | |
| G | Ser | Ser | Arg | Arg | |
| G | U | Val | Val | Val | Val |
| C | Ala | Ala | Ala | Ala | |
| A | Asp | Asp | Glu | Glu | |
| G | Gly | Gly | Gly | Gly | |
Leu-Thr-Ser-Gly-Ser-Pro
Related Answered Questions
Question: 24.1
Verified Answer:
Original: (5′) TATGCAT (3′)
Complement: (3′) ATACG...