Organic Chemistry with Biological Applications 2nd. Edition by John E. McMurry | 9780495391449 | 0495391441 | Holooly

Biological Chemistry, Organic Chemistry

Organic Chemistry with Biological Applications

84 SOLVED PROBLEMS

Question: 2.5

Calculating Ka from pKa According to the data in Table 2.3, acetic acid has pKa = 4.76. What is its Ka? ...

Verified Answer:

K_{a}=1.74 \times 10^{-5}

Question: 11.3

Predicting Chemical Shifts in 1H NMR Spectra Methyl 2,2-dimethylpropanoate (CH3)3CCO2CH3 has two peaks in its 1H NMR spectrum. What are their approximate chemical shifts? ...

Verified Answer:

The –OCH3 protons absorb around 3.5 to

4.0 ...

Question: 10.5

Predicting IR Absorptions of Compounds Where might the following compounds have IR absorptions? ...

Verified Answer:

(a) This molecule has an alcohol O–H group and an ...

Question: 10.4

Distinguishing Isomeric Compounds by IR Spectroscopy Acetone (CH3COCH3) and prop-2-en-1-ol (H2C=CHCH2OH) are isomers. How could you distinguish them by IR spectroscopy? ...

Verified Answer:

Acetone has a strong C=O absorption at 1715 [latex...

Question: 4.3

Drawing the Most Stable Conformation of a Substituted Cyclohexane Draw the most stable conformation of cis-1-tert-butyl-4-chlorocyclohexane. By how much is it favored? ...

Verified Answer:

First draw the two chair conformations of the mole...

Question: 10.1

Using Mass Spectra to Identify Compounds Assume that you have two unlabeled samples, one of methylcyclohexane and the other of ethylcyclopentane. How could you use mass spectrometry to identify them? The mass spectra of both are shown in Figure 10.6. ...

Verified Answer:

The mass spectra of both samples show molecular io...

Question: 24.2

Predicting the Amino Acid Sequence Transcribed from DNA What amino acid sequence is coded by the following segment of a DNA sense strand? (5′) CTA-ACT-AGC-GGG-TCG-CCG (3′) ...

Verified Answer:

Leu-Thr-Ser-Gly-Ser-Pro

Question: 24.1

Predicting the Complementary Base Sequence in Double-Stranded DNA What sequence of bases on one strand of DNA is complementary to the sequence TATGCAT on another strand? ...

Verified Answer:

Original: (5′) TATGCAT (3′) Complement: (3′) ATACG...

Question: 16.1

Predicting the Product of a Nucleophilic Acyl Substitution Reaction Predict the product of the following nucleophilic acyl substitution reaction of benzoyl chloride with propan-2-ol: ...

Verified Answer:

Question: 15.1

Predicting the Effect of a Substituent on the Reactivity of an Aromatic Ring toward Electrophilic Substitution The pKa of p-(trifluoromethyl)benzoic acid is 3.6. Is the trifluoromethyl substituent an activating or deactivating group in electrophilic aromatic substitution? ...

Verified Answer:

A

pK_{a}

of 3.6 means that p-(trif...

Loading...