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Question 24.2: Predicting the Amino Acid Sequence Transcribed from DNA What...

Predicting the Amino Acid Sequence Transcribed from DNA

What amino acid sequence is coded by the following segment of a DNA sense strand?

(5′) CTA-ACT-AGC-GGG-TCG-CCG (3′)

Strategy
The mRNA produced during translation is a copy of the DNA sense strand, with each T replaced by U. Thus, the mRNA has the sequence
(5′) CUA-ACU-AGC-GGG-UCG-CCG (3′)
Each set of three bases forms a codon, whose meaning can be found in Table 24.1.

TABLE 24.1
Codon Assignments of Base Triplets
Third base (3′ end)
First base (5′ end) Second base U C A G
U U Phe Phe Leu Leu
C Ser Ser Ser Ser
A Tyr Tyr Stop Stop
G Cys Cys Stop Trp
C U  Leu  Leu  Leu  Leu
C Pro Pro Pro Pro
A His His Gln Gln
G Arg Arg Arg Arg
A U Ile Ile Ile Met
C Thr Thr Thr Thr
A Asn Asn Lys Lys
G Ser Ser Arg Arg
G U Val Val Val Val
C Ala Ala Ala Ala
A Asp Asp Glu Glu
G Gly Gly Gly Gly
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Question: 24.1

Predicting the Complementary Base Sequence in Double-Stranded DNA What sequence of bases on one strand of DNA is complementary to the sequence TATGCAT on another strand? ...

Verified Answer:

Original: (5′) TATGCAT (3′) Complement: (3′) ATACG...