Question 16.1: Predicting the Product of a Nucleophilic Acyl Substitution R...

Organic Chemistry with Biological Applications

Predicting the Product of a Nucleophilic Acyl Substitution Reaction

Predict the product of the following nucleophilic acyl substitution reaction of benzoyl chloride with propan-2-ol:

Strategy
A nucleophilic acyl substitution reaction involves the substitution of a nucleophile for a leaving group in a carboxylic acid derivative. Identify the leaving group ( $Cl^{-}$ in the case of an acid chloride) and the nucleophile (an alcohol in this case), and replace one by the other. The product is isopropyl benzoate.

The blue check mark means that this solution has been answered and checked by an expert. This guarantees that the final answer is accurate.
Learn more on how we answer questions.